Services
We bring expertise in all aspects of membrane protein production, structural biology, and hit discovery. Our cutting-edge technologies, collaborative approach, and flexible contract options are tailored to meet your specific research and drug discovery needs. We also offer free feasibility assessments to ensure we’re the right partner for your project.
Protein Sciences
We deliver high-quality proteins tailored to your needs, combining cutting-edge technologies with our deep expertise in construct design, expression, and purification. Our streamlined processes ensure precision, scalability, and reliability.
What we offer:
- Gene-to-protein services
- Off-the-shelf proteins (90+, list upon request)
- Construct engineering and optimization
- Purity, homogeneity, stability, and functional testing
Curious about our expertise? Contact us to discover the range of proteins we’ve successfully worked with and how we can support your project.
Biophysical Characterization of Membrane Proteins
Uncover the critical data you need to make informed decisions with our advanced biophysical characterization services. Using state-of-the-art tools, we provide actionable insights into molecular interactions and stability.
What we offer:
- Characterization and quantification of client compounds for target engagement, affinity, kinetics, competition, allosteric modulation, thermodynamics (GCI, MST/TRIC, MS)
- Protein thermal stability / thermal shift assays (DSF, nanoDSF, CPM, FSEC-TS)
- Molecular and particle sizing, oligomerization, aggregation (DLS, SLS)
- Nanobody/antibody binding characterization (GCI, analytical SEC)
Discover how our cutting-edge technologies, like Grating-Coupled Interferometry (GCI), elevate biophysical assay precision. Learn more about our approach on the Technology Platform.
Structural Biology
Solve the most complex structural challenges with our expertise in structural biology. From initial grid freezing to high-resolution structure determination, we provide comprehensive support for your projects.
What we offer:
- X-ray crystallography and CryoEM services
- Negative staining EM
- Cryo-EM grid freezing optimization
- Crystallization screening and structure refinement
- Serial and time-resolved crystallography
Discover how our structural biology expertise delivers results. From advancing GPCR drug discovery to solving transporter and ion channel structures, and leveraging free elector lasers for groundbreaking insights—our case studies showcase the impact we can achieve together.
Computational Chemistry
Accelerate discovery with our advanced computational chemistry services. We bridge in silico insights with experimental validation to drive results faster and more efficiently.
What we offer:
- Structure-based virtual screening using ultra-large combinatorial libraries
- Binding pose modeling using induced fit docking and free energy methods
- Structure-based drug design
- Ligand-protein interaction analysis
- In-silico mutagenesis for protein engineering
See our computational chemistry in action. Explore our vision to learn how we identified high-quality hits from ultra-large libraries, driving faster and more efficient drug discovery.
Lead Discovery
Take your discovery projects from hit identification to lead optimization with our integrated approach. Combining medicinal, synthetic, and computational chemistry with biophysical and structural insights, we guide you every step of the way.
What we offer:
- Hit-to-lead optimization
- Lead candidate selection
- Multi-disciplinary project management
Discover how we advanced the GPR68 project in collaboration with Cumulus Oncology. Explore our case study to see how we supported the hit-to-lead process and optimized candidates for impactful drug discovery.
Need more reasons?
Here are some of the reasons why our partners love working with us:
Confidentiality
IP and Target Exclusivity
Expert Membrane Protein Scientists
Expertise in Membrane Proteins
Flexible Contracts
Unique Technologies