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leadXpro

“We unlock tomorrow’s medicines together, better, faster.”

At leadXpro, we are committed to accelerating the discovery of life-changing medicines. Driven by our passion for innovation and cutting-edge science, we specialize in structure-based drug discovery, with a laser focus on membrane proteins. Working together with our clients, we aim to transform our science into therapies—better and faster.

Core Expertise

Our expertise lies in unlocking the potential of membrane proteins, important yet challenging targets in drug discovery. Through advanced methods such as CryoEM, time resolved X-ray crystallography, and ultra-large virtual screening, we provide a comprehensive platform to support pharmaceutical innovation. From early-stage discovery to lead optimization, we empower researchers to accelerate breakthroughs in medicine.

Track Record

  • Over 10 years of experience in structure-based drug discovery.
  • Delivering Swiss quality over 10 years of experience in structure-based drug discovery.
  • Successfully collaborated on 150+ projects on over 90 different membrane proteins with leading biotech and pharmaceutical companies.
  • Published in top-tier scientific journals, advancing the field of membrane protein research.
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Philosophy

At the heart of our work is a commitment to collaboration, excellence, and innovation. We believe success is a shared journey, driven by open communication and diverse perspectives. With unwavering determination, we embrace scientific challenges to deliver impactful results and build lasting partnerships. Excellence is our standard, achieved through continuous improvement, persistence, and precision. By fostering a mindset of innovation and challenging the status quo, we turn scientific discoveries into transformative applications. Together, we strive to make a meaningful impact on structure-based drug discovery for membrane proteins.

Team

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Our state-of-the-art labs

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Our new, state-of-the-art lab, opened in 2024 at Park Innovaare in Villigen, Switzerland, is equipped to support cutting-edge research in protein expression and purification, biophysical assays, crystallization, and grid freezing. With advanced facilities and the latest technologies, we provide a fully integrated environment that accelerates every stage of your research and drug discovery process. Our lab is designed for high throughput and precision, ensuring reliable, high-quality results for your most demanding projects.

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Founders

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Gebhard Schertler

Membrane Protein Science Expert

Biochemist, group leader Structural Biology of Membrane Proteins at PSI. Previously member of the PSI Directorial Board.

Michael Henning

Michael Hennig

CEO, Chairman of the Board

Structural biologist and senior drug discovery executive. Previously, global head of Discovery Technologies at Roche.

Rafael Abela

Rafael Abela

Board Member

Physicist, scientific advisor at PSI. Previously, scientific project leader for the SLS and SwissFEL projects at PSI, laboratory head at SLS and SwissFEL.

Board of Directors

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Michael Milos

Board Member

Molecular biologist, University Vienna and Brain Research Institute at University Zürich, managing partner at AVANTECA Partners AG.

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John Millard

Board Member

Serial entrepreneur, head of Technology Transfer Management at PSI, Swiss representative CERN KT Forum and board member of swiTT.

Andreas Insam

Andreas Insam

Board Member

Business economist, board member of XRnanotech, settlor INSAM Familienstiftung. Previously CEO of the BENDURA BANK in Liechtenstein.

  • Michael Hennig as Chairman of the Board
  • Rafael Abela as Board Member