About us – leadXpro

leadXpro

“We unlock tomorrow’s medicines together, better, faster.”

At leadXpro, we are committed to accelerating the discovery of life-changing medicines. Driven by our passion for innovation and cutting-edge science, we specialize in structure-based drug discovery, with a laser focus on membrane proteins. Working together with our clients, we aim to transform our science into therapies—better and faster.

Core Expertise

Our expertise lies in unlocking the potential of membrane proteins, important yet challenging targets in drug discovery. Through advanced methods such as CryoEM, time resolved X-ray crystallography, and ultra-large virtual screening, we provide a comprehensive platform to support pharmaceutical innovation. From early-stage discovery to lead optimization, we empower researchers to accelerate breakthroughs in medicine.

Track Record

Over 10 years of experience in structure-based drug discovery.
Delivering Swiss quality over 10 years of experience in structure-based drug discovery.
Successfully collaborated on 150+ projects on over 90 different membrane proteins with leading biotech and pharmaceutical companies.
Published in top-tier scientific journals, advancing the field of membrane protein research.

Philosophy

At the heart of our work is a commitment to collaboration, excellence, and innovation. We believe success is a shared journey, driven by open communication and diverse perspectives. With unwavering determination, we embrace scientific challenges to deliver impactful results and build lasting partnerships. Excellence is our standard, achieved through continuous improvement, persistence, and precision. By fostering a mindset of innovation and challenging the status quo, we turn scientific discoveries into transformative applications. Together, we strive to make a meaningful impact on structure-based drug discovery for membrane proteins.

Team

Our state-of-the-art labs

Our new, state-of-the-art lab, opened in 2024 at Park Innovaare in Villigen, Switzerland, is equipped to support cutting-edge research in protein expression and purification, biophysical assays, crystallization, and grid freezing. With advanced facilities and the latest technologies, we provide a fully integrated environment that accelerates every stage of your research and drug discovery process. Our lab is designed for high throughput and precision, ensuring reliable, high-quality results for your most demanding projects.

Founders

Gebhard Schertler

Membrane Protein Science Expert

Biochemist, group leader Structural Biology of Membrane Proteins at PSI. Previously member of the PSI Directorial Board.

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Gebhard completed his PhD at the University of Münich focusing on structural biology of membrane proteins and molecular pharmacology. After leading the MRC laboratory of molecular biology at the University of Cambridge he moved to Switzerland where he held the head positions of the Laboratory of Biomolecular Research and the Division of Biology and Chemistry at PSI, including a full professorship of Structural Biology at ETH Zürich.

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Michael Hennig

CEO, Chairman of the Board

Structural biologist and senior drug discovery executive. Previously, global head of Discovery Technologies at Roche.

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After his PhD at the EMBL Hamburg and postdoc at the Biozentrum of the University of Basel Michael looks back to 20 years of drug discovery expertise in structural biology and research management at Roche AG Basel. He contributed to the delivery of Tamiflu, Fortovase, Xenical, Carmegliptin, Aleglitazar and is author of more than 70 articles and 8 patents. Additionally, he holds a guest professorship position for structural biology at the University of Basel.

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