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leadXpro

“We unlock tomorrow’s medicines together, better, faster.”

At leadXpro, we are committed to accelerating the discovery of life-changing medicines. Driven by our passion for innovation and cutting-edge science, we specialize in structure-based drug discovery, with a laser focus on membrane proteins. Working together with our clients, we aim to transform our science into therapies—better and faster.

Core Expertise

Our expertise lies in unlocking the potential of membrane proteins, important yet challenging targets in drug discovery. Through advanced methods such as CryoEM, time resolved X-ray crystallography, and ultra-large virtual screening, we provide a comprehensive platform to support pharmaceutical innovation. From early-stage discovery to lead optimization, we empower researchers to accelerate breakthroughs in medicine.

Track Record

  • Over 10 years of experience in structure-based drug discovery.
  • Delivering Swiss quality over 10 years of experience in structure-based drug discovery.
  • Successfully collaborated on 150+ projects on over 100 different membrane proteins with leading biotech and pharmaceutical companies.
  • Published in top-tier scientific journals, advancing the field of membrane protein research.
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Team

At the heart of our work is a commitment to collaboration, excellence, and innovation. We believe success is a shared journey, driven by open communication and diverse perspectives. With unwavering determination, we embrace scientific challenges to deliver impactful results and build lasting partnerships. Excellence is our standard, achieved through continuous improvement, persistence, and precision. By fostering a mindset of innovation and challenging the status quo, we turn scientific discoveries into transformative applications. Together, we strive to make a meaningful impact on structure-based drug discovery for membrane proteins.

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Our state-of-the-art labs

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Our new, state-of-the-art lab, opened in 2024 at Park Innovaare in Villigen, Switzerland, is equipped to support cutting-edge research in protein expression and purification, biophysical assays, crystallization, and grid freezing. With advanced facilities and the latest technologies, we provide a fully integrated environment that accelerates every stage of your research and drug discovery process. Our lab is designed for high throughput and precision, ensuring reliable, high-quality results for your most demanding projects.

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Sustainability

As a biotechnology company with worldwide activities, sustainability is central to our mission and reflects the expectations of our employees, partners, and clients. By embedding ethical science and work practice, responsible resource use, and transparent operations, we aim to reduce our environmental footprint and create lasting value.

A double materiality analysis helped us identify three key impact areas: upholding scientific integrity and fostering innovation strengthen our reputation and credibility, attracting talented individuals and nurturing a positive organizational culture, and improving operational efficiency to minimize our environmental impact. Guided by our values of commitment, collaboration, impact, innovation, and excellence, we strive to create meaningful outcomes for patients, our employees, and the planet. Our primary Environmental, Social, and Governance (ESG) objectives, aligned with these impact areas, are illustrated in the figure below.

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We also participate in the EcoVadis sustainability assessment, where we were recently awarded the Bronze Medal, recognizing our commitment to responsible business practices and continuous improvement in sustainability.

Careers

Join us to push the boundaries of structure-based drug discovery and design medicines that matter. Check out our open positions here.

Partners

At the heart of our success is our collaboration with a diverse network of industry leaders, academic institutions, and technology innovators. Together, we tackle the most complex challenges in drug discovery.

Founders and Board of Directors

Gebhard Schertler, Co-Founder
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Michael Hennig, CEO, Co-Founder and Board Member
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Rafael Abela, Co-Founder and Board Member
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Michael Milos, Board Member
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John Millard, Board Member
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Andreas Insam, Board Member
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Oliver Nayler, Board Member
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