
Cryo-EM structure of active GPR65 leadXpro has just elucidated the world’s first structure of a proton-sensing GPCR target.

ABOUT leadXpro
Welcome to leadXpro, where we specialize in structure-based drug discovery for membrane proteins. Our team of experts brings together knowledge in membrane protein science, pioneering technologies in structural biology, and expertise in ligand design and characterization to help our clients develop new and innovative therapies.
At leadXpro, we are dedicated to helping our clients unlock the potential of membrane proteins to improve human health. Our research covers a range of membrane proteins, including GPCRs, ion channels, transporters, and enzymes, giving us a unique and comprehensive perspective on the drug discovery target space.
But we don’t just stop at research. As a contract research partner, we offer a variety of services and partnership models to a growing number of pharmaceutical, biotech, and academic partners. Our flexible approach allows us to work with clients at every stage of their drug discovery project, from hit finding and validation, to structure-based optimization of preclinical compounds.
So if you’re looking to make a breakthrough in drug discovery, look no further than leadXpro. Contact us today to learn more about how we can help you achieve your goals.
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THERAPEUTICS
Using its unique technology platform, leadXpro is developing proprietary preclinical compounds with high efficacy and specificity.
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Latest updates about leadXpro
SCIENTIFIC WEBINAR
Early drug discovery requires an interdisciplinary approach with a sophisticated interplay between empirical methods and rational design. Amongst the different therapeutic modalities, orally available small molecules are a major pillar for safe treatment of acute and chronic diseases.
RaQualia Pharma and leadXpro Announce Collaboration to Accelerate Drug Discovery on Intractable Membrane Protein Targets
In this collaboration, leadXpro will establish robust protocols and workflows to facilitate the rapid determination
Septerna Engages leadXpro to Discover Novel Binding Partners to GPCR Targets for use in Internal Drug Discovery Programs
During this engagement, leadXpro will use membrane proteins selected by Septerna to discover novel binding partners to…
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