Cryo-EM structure of active GPR65 leadXpro has just elucidated the world’s first structure of a proton-sensing GPCR target.
Welcome to leadXpro, where we specialize in structure-based drug discovery for membrane proteins. Our team of experts brings together knowledge in membrane protein science, pioneering technologies in structural biology, and expertise in ligand design and characterization to help our clients develop new and innovative therapies.
At leadXpro, we are dedicated to helping our clients unlock the potential of membrane proteins to improve human health. Our research covers a range of membrane proteins, including GPCRs, ion channels, transporters, and enzymes, giving us a unique and comprehensive perspective on the drug discovery target space.
But we don’t just stop at research. As a contract research partner, we offer a variety of services and partnership models to a growing number of pharmaceutical, biotech, and academic partners. Our flexible approach allows us to work with clients at every stage of their drug discovery project, from hit finding and validation, to structure-based optimization of preclinical compounds.
So if you’re looking to make a breakthrough in drug discovery, look no further than leadXpro. Contact us today to learn more about how we can help you achieve your goals.
Latest updates about leadXpro
We are delighted to share the exciting news that Juana Lucia Flores-Candia, esteemed Board Member at leadXpro AG, is set to grace the stage at our forthcoming 2nd Ace Drug Discovery Summit (ADDS) at The Insurance Hall in London on the 20th and 21st of March 2024.Don’t miss the opportunity to be part of the […]
Cumulus Oncology and leadXpro Announce Collaboration to Develop Small Molecules against Novel Cancer-Focused GPCR Targets
Cumulus Oncology and leadXpro Announce Collaboration.
Resulting IP will be licensed into a newly created Cumulus company
Early drug discovery requires an interdisciplinary approach with a sophisticated interplay between empirical methods and rational design. Amongst the different therapeutic modalities, orally available small molecules are a major pillar for safe treatment of acute and chronic diseases.